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Curriculum
1994 BS in Biochemistry, Stony Brook University, Stony Brook, NY
2001 PhD in Cellular and Developmental Biology, Jim Trimmer Laboratory Brook University, Stony Brook, NY
2004 MD with Disctintion in Research, Stony Brook University, Stony Brook, NY
2004-2006 Postdoctoral Fellow, Grigori Enikolopov Lab, Cold Spring Harbor Laboratory, NY
2006-2007 Postdoctoral Associate, Mirjana Maletic-Savatic Lab, Stony Brook University, NY
Awards
1993-1994 Golden Key Honor Society
1999 First place Graduate Student Presentation Award, American Physiological Society Conference
2001 Excellence in Graduate Research Award, Institute for Cellular and Developmental Biology, Stony Brook University, NY
2004 MD with Disctintion in Research, Stony Brook University, NY
2007 Top 5% presentation (selected for Webcast-on-Demand), American Academy of Neurology Meeting
Publications
Manganas LN, Encinas JM, Enikolopov G and Maletic-Savatic M. (In preparation). Generation and Characterization of Monoclonal Antibodies to Neurospheres.
Manganas LN, Zhang X, Li Y, Hazel RD, Smith DS, Wagshul ME, Benveniste H, Djuric PM, Enikolopov G, Maletic-Savatic M. 2007. Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science 318:980-985
Mignone JL, Roig-Lopez JL, Fedtsova N, Schones DE, Manganas LN, Maletic-Savatic M, Keyes WM, Mills AA, Gleiberman A, Zhang MQ, Enikolopov G. 2007. Neural potential of a stem cell population in the hair follicle. Cell Cycle 6(17):216170
El-Helou V, Dupuis J, Proulx C, Drapeau J, Clement R, Gosselin H, Villeneuve L, Manganas LN and Calderone A. 2005. Resident nestin (+) neural cells and fibre-like structures detected in the normal rat myocardium. Hypertension;46(5):1219-25.
Manganas LN and Maletic-Savatic M. 2005. Stem Cell Therapy for C NS Demyelinating Diseases. Current Neurology and Neuroscience Reports 5(3):225-31.
Encinas JM, Manganas LN and Enikolopov G. 2005. Nitric Oxide and CNS Injury. Current Neurology and Neuroscience Reports 5(3):232-8.
Manganas LN and Trimmer JS. 2004. Calnexin regulates mammalian Kv1 channel trafficking. Biochemical and Biophysical Research Communications 322(2):577-84.
Campomanes CR, Carroll KI, Manganas LN, Hershberger ME, Gong B, Antonucci DE, Rhodes KJ and Trimmer JS. 2002. Kv?Beta Subunit Oxidoreductase Activity and Kv1 Potassium Channel Trafficking. Journal of Biological Chemistry 277(10):8298-8305
Manganas LN, Akhtar S, Antonucci DE, Campomanes CR, Oliver Dolly J and Trimmer JS. 2001. Episodic Ataxia Type-1 Mutations in the Kv1.1 Potassium Channel Display Distinct Folding and Intracellular Trafficking Properties. Journal of Biological Chemistry, 276 (52):49427-49434
Manganas LN, Wang Q, Scannevin RH, Antonucci DE, Rhodes KJ and Trimmer JS. 2001. Identification of a Trafficking Determinant Localized to the Kv1 Potassium Channel Pore. Proceedings of the National Academy of Science 98 (24):14055-14059
Manganas LN and Trimmer JS. 2000. Subunit Composition Determines Kv1 Potassium Channel Surface Expression. Journal of Biological Chemistry 275(38):29685- 29693
Tiffany AF, Manganas LN, Kim E, Sheng M and Trimmer JS. 2000. PSD-95 and SAP-97 Exhibit Distinct Mechanisms for Regulating K+ Channel Surface Expression and Clustering. Journal of Cell Biology 148(1):147-157
Bekele-Arcuri Z, Matos MF, Manganas LN, Strassle BW, Monaghan MM, Rhodes KJ and Trimmer JS. 1996. Generation and Characterization of Subtype-Specific Monoclonal Antibodies to K+ Channel Alpha and Beta Subunit Polypeptides. Neuropharmacology 35:851-865